Bending the Curve of Global Freshwater Biodiversity Loss: An Emergency Recovery Plan.

Bending the Curve of Global Freshwater Biodiversity Loss: An Emergency Recovery Plan.

Despite their restricted spatial extent, freshwater ecosystems host exceptional biodiversity, together with one-third of all vertebrate species. This biodiversity is declining dramatically: Globally, wetlands are vanishing 3 times quicker than forests, and freshwater vertebrate populations have fallen greater than twice as steeply as terrestrial or marine populations.

Threats to freshwater biodiversity are properly documented however coordinated motion to reverse the decline is missing. We current an Emergency Recovery Plan to bend the curve of freshwater biodiversity loss. Priority actions embody accelerating implementation of environmental flows; enhancing water high quality; defending and restoring important habitats; managing the exploitation of freshwater ecosystem sources, particularly species and riverine aggregates; stopping and controlling nonnative species invasions; and safeguarding and restoring river connectivity.

We suggest changes to targets and indicators for the Convention on Biological Diversity and the Sustainable Development Goals and roles for nationwide and worldwide state and nonstate actors.

Bending the Curve of Global Freshwater Biodiversity Loss: An Emergency Recovery Plan.
Bending the Curve of Global Freshwater Biodiversity Loss: An Emergency Recovery Plan.

Biodiversity Survey of Flower-Visiting Spiders Based on Literature Review and Field Study.

Many arthropods exhibit flower-visiting habits, together with a spread of spider species. However, as spiders are assumed to be strictly predatory, flower-visiting spiders are an typically uncared for group. We carried out a scientific biodiversity research of flower-visiting spiders primarily based on revealed papers and discipline surveys. Most earlier research have centered on the herbivorous habits of flower-visiting spiders (nectivory or pollinivory) and their results on host flowers (tritrophic interactions with flower-visiting bugs).

In our discipline survey, we utilized customary transect walks (energetic sampling) and coloured pan traps (passive sampling) to analyze species prevalence, diurnal and seasonal variation, and flower shade desire of flower-visiting spiders. From the transect walks, crab spider species had been discovered to be the dominant flower-visiting spiders and, primarily based on all spider species, juvenile guests had been considerably extra frequent than adults. Furthermore, in phrases of spider quantity and species richness, tulips had been the most well-liked flower to go to.

NMDA receptor antagonist-3

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Description: NMDA receptor antagonist-3

NMDA receptor antagonist-3

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Description: NMDA receptor antagonist-3

NMDA receptor antagonist 2

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Description: NMDA receptor antagonist 2 is a potent and orally active NR2B subtype-selective NMDA antagonist with an IC50 and a Ki of 1.0 nM and 0.88 nM, respectively. NMDA receptor antagonist 2 is used for the study of neuropathic pain and Parkinson’s disease[1].

NMDA receptor antagonist 6

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Description: NMDA receptor antagonist 6 (compound 13b) is an antagonist of NMDA receptor, targeting to the glycine binding site. NMDA receptor antagonist 6 shows cytoneuroprotective potency, and protects PC12 cells against NMDA-induced injury and cell apoptosis[1].

NMDA receptor antagonist 7

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Description: NMDA receptor antagonist 7 (Compound (S)-10a) is GluN2B subunit-selective NMDA Receptor antagonist, with an Ki of 93 nM and an IC50 of 72 nM. NMDA receptor antagonist 7 can be used for research of neurodegenerative diseases[1].

NMDA receptor antagonist 8

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Description: NMDA receptor antagonist 8 (Compound (R)-10a) is GluN2B subunit-selective NMDA Receptor antagonist, with an Ki of 265 nM and an IC50 of 62 nM. NMDA receptor antagonist 8 can be used for research of neurodegenerative diseases[1].

NMDA receptor antagonist 5

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Description: NMDA receptor antagonist 5 (Compound 10e) is a potent, brain permeable and non-toxic NMDA receptor antagonist. NMDA receptor antagonist 5 can be used for neurological disorder research[1].

NMDA receptor antagonist 4

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Description: NMDA receptor antagonist 4 (IIc) is a uncompetitive, voltage-dependent, orally active NMDAR blocker, with an IC50 of 1.93 µM. NMDA receptor antagonist 4 shows a positive predicted blood-brain-barrier (BBB) permeability, and can be studied in Alzheimer's disease[1].

NMDA receptor antagonist 2

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NMDA receptor antagonist 2

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NMDA receptor antagonist 2

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Description: NMDA receptor antagonist 2

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Description: NMDA receptor antagonist 2

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Description: NMDA receptor antagonist 2

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Description: NMDA receptor antagonist 2

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Description: NMDA receptor antagonist 2

NMDA receptor antagonist 4

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Description: NMDA receptor antagonist 4

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Description: NMDA receptor antagonist 4

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Description: NMDA receptor antagonist 4

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Description: NMDA receptor antagonist 4

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Description: NMDA receptor antagonist 4

NMDA receptor antagonist 5

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Description: NMDA receptor antagonist 5

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Description: NMDA receptor antagonist 5

NMDA receptor antagonist 5

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Description: NMDA receptor antagonist 5

NMDA receptor antagonist 5

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Description: NMDA receptor antagonist 5

NMDA receptor antagonist 5

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Description: NMDA receptor antagonist 5

PMPA (NMDA antagonist)

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Description: Membrane Transporter/Ion Channel|NMDA Receptor

PMPA (NMDA antagonist)

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Description: Membrane Transporter/Ion Channel|NMDA Receptor

PMPA (NMDA antagonist)

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Description: PMPA (NMDA antagonist) is an NMDA receptor antagonist with Ki values of 0.84, 2.74, 3.53 and 4.16 μM for NR2A, NR2B, NR2C and NR2D, respectively[1].

PMPA (NMDA antagonist)

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PMPA (NMDA antagonist)

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PMPA (NMDA antagonist)

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Description: 113919-36-1

PMPA (NMDA antagonist)

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Description: PMPA (NMDA antagonist)

PMPA (NMDA antagonist)

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Description: PMPA (NMDA antagonist)

PMPA (NMDA antagonist)

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Description: PMPA (NMDA antagonist)

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Description: PMPA (NMDA antagonist)

PMPA (NMDA antagonist)

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Description: PMPA (NMDA antagonist)

VIP Receptor Antagonist

064-22 PHOENIX PEPTIDE 200 μg 114.48 EUR

σ1 Receptor antagonist-1

HY-10815 MedChemExpress 1 mg 619.06 EUR
Description: σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells[1].

σ1 Receptor antagonist-1

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Description: σ1 Receptor antagonist-1

σ1 Receptor antagonist-1

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Description: σ1 Receptor antagonist-1

σ1 Receptor antagonist-1

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Description: σ1 Receptor antagonist-1

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Description: σ1 Receptor antagonist-1

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Description: σ1 Receptor antagonist-1

EP2 receptor antagonist-2

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Description: EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor. EP2 receptor antagonist-2 inhibits the EP2 receptor activation induced by PGE2. EP2 receptor antagonist-2 also suppresses lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA)[1].

LPA receptor antagonist-1

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Description: LPA receptor antagonist-1 (example 52) is an antagonist of lysophosphatidic acid (LPA) receptor. LPA receptor antagonist-1 can be used for kinds of studies[1].

EP2 receptor antagonist-1

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Description: EP2 receptor antagonist-1 (compound 1) is a potent, reversible, and agonist dependent allosteric prostaglandin EP2 receptor antagonist. EP2 receptor antagonist-1 shows anti-inflammatory effects[1].

EP2 receptor antagonist-1

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Description: EP2 receptor antagonist-1

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Description: EP2 receptor antagonist-1

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Description: EP2 receptor antagonist-1

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Description: EP2 receptor antagonist-1

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Description: EP2 receptor antagonist-1

Opioid receptor antagonist

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Description: Ac-Arg-Phe-Met-Trp-Met-Lys-NH2

Opioid receptor antagonist

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Opioid receptor antagonist

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Opioid receptor antagonist

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Opioid receptor antagonist

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Opioid receptor antagonist

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AMPA receptor antagonist-2

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Description: AMPA receptor antagonist-2 (example 23) is an AMPA receptor antagonist[1].

P2X7 receptor antagonist-2

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Description: P2X7 receptor antagonist-2 is a potent P2X7 receptor antagonist with a pIC50 value of 6.5-7.5. P2X7 receptor antagonist-2 has efficacy of combating neuroinflammation[1].

P2X7 receptor antagonist-4

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Description: P2X7 receptor antagonist-4 (Compound 14a) is a P2X7R antagonist. The P2X7 receptor antagonist-4 values of P2X7R IC50 in human and mouse are 64.7 and 10.1 nM, respectively. P2X7 receptor antagonist-4 can inhibit the activation of NLRP3 inflammasome, thereby inhibiting the expression of caspase-1, gasdermin D, IL-1β and IL-18 in the damaged kidney of sepsis mice[1].

CRF1 receptor antagonist-1

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Description: CRF1 receptor antagonist-1 (Compound 2) is a CRF1 receptor antagonist. CRF1 receptor antagonist-1 can be used for research of congenital adrenal hyperplasia (CAH)[1].

AMPA receptor antagonist-3

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Description: AMPA receptor antagonist-3 is an AMPA receptor antagonist extracted from patent US20070027143A1. AMPA receptor antagonist-3 can be used for the research of central nervous system disorders[1].

P2X7 receptor antagonist-3

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Description: P2X7 receptor antagonist-3 is a potent P2X7 receptor antagonist with P2X7R IC50 values of 4.2 nM in humans and 6.8 nM in rats[1].

P2X7 receptor antagonist-2

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Description: P2X7 receptor antagonist-2

P2X7 receptor antagonist-2

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Description: P2X7 receptor antagonist-2

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Description: P2X7 receptor antagonist-2

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Description: P2X7 receptor antagonist-2

P2X7 receptor antagonist-2

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Description: P2X7 receptor antagonist-2

AMPA receptor antagonist-3

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Description: AMPA receptor antagonist-3

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Description: AMPA receptor antagonist-3

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Description: AMPA receptor antagonist-3

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Description: AMPA receptor antagonist-3

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Description: AMPA receptor antagonist-3

P2X7 receptor antagonist-1

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Description: P2X7 receptor antagonist-1

P2X7 receptor antagonist-1

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Description: P2X7 receptor antagonist-1

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Description: P2X7 receptor antagonist-1

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Description: P2X7 receptor antagonist-1

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Description: P2X7 receptor antagonist-1

AMPA receptor antagonist-2

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Description: AMPA receptor antagonist-2

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Description: AMPA receptor antagonist-2

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Description: AMPA receptor antagonist-2

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Description: AMPA receptor antagonist-2

AMPA receptor antagonist-2

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Description: AMPA receptor antagonist-2

Thrombin Receptor Antagonist

H-2514.0500 Bachem 0.5mg 211.2 EUR
Description: Sum Formula: C58H91N17O20S2; CAS# [207553-92-2]

Thrombin Receptor Antagonist

H-2514.1000 Bachem 1.0mg 327.6 EUR
Description: Sum Formula: C58H91N17O20S2; CAS# [207553-92-2]

sigma1 Receptor antagonist-1

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sigma1 Receptor antagonist-1

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sigma1 Receptor antagonist-1

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sigma1 Receptor antagonist-1

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sigma1 Receptor antagonist-1

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H3 receptor antagonist 1

HY-U00269 MedChemExpress 10mg 1746 EUR

Y1 receptor antagonist 1

HY-101704 MedChemExpress 1mg 464.29 EUR
Description: Y1 receptor antagonist 1 (H 409-22 isomer) is a neuropeptide Y1 receptor antagonist.

H4 Receptor antagonist 1

HY-114025 MedChemExpress 10mg 530.31 EUR
Description: H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.

ET receptor antagonist 1

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Description: ET receptor antagonist 1 (compound 16h) is an orally active ET receptor antagonist (IC50=0.18 nM), which can be used for research in pulmonary arterial hypertension (PAH). ET receptor antagonist 1 attenuates monocrotaline (HY-N0750) induced PAH in rat model[1].

ET receptor antagonist 2

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Description: ET receptor antagonist 2 (compound 16j) is an orally active ET receptor antagonist (IC50=0.22 nM), which can be used for research in pulmonary arterial hypertension (PAH). ET receptor antagonist 2 attenuates monocrotaline (HY-N0750) induced PAH in rat model[1].

ET receptor antagonist 3

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Description: ET receptor antagonist 3 (compound 17d) is an orally active ET receptor antagonist (IC50=0.26 nM), which can be used for research in pulmonary arterial hypertension (PAH). ET receptor antagonist 3 attenuates monocrotaline (HY-N0750) induced PAH in rat model[1].

H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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Y1 receptor antagonist 1

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Y1 receptor antagonist 1

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H3 receptor antagonist 1

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H3 receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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Y1 receptor antagonist 1

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Y1 receptor antagonist 1

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Y1 receptor antagonist 1

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Y1 receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H4 Receptor antagonist 1

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H3 receptor antagonist 1

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Description: H3 receptor antagonist 1

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Description: H3 receptor antagonist 1

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Description: H3 receptor antagonist 1

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Description: H3 receptor antagonist 1

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Description: H3 receptor antagonist 1

Y1 receptor antagonist 1

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Description: Y1 receptor antagonist 1

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Description: Y1 receptor antagonist 1

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Description: Y1 receptor antagonist 1

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Description: Y1 receptor antagonist 1

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Description: Y1 receptor antagonist 1

H4 Receptor antagonist 1

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Description: H4 Receptor antagonist 1

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Description: H4 Receptor antagonist 1

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Description: H4 Receptor antagonist 1

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Description: H4 Receptor antagonist 1

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Description: H4 Receptor antagonist 1

EP4 Receptor Antagonist 1

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EP4 receptor antagonist 2

HY-136645 MedChemExpress Get quote Ask for price
Description: EP4 receptor antagonist 2 (compound 2-13) is a potent EP4 receptor antagonist with an IC50 of 7.8 nM. EP4 receptor antagonist 2 shows antitumor activity[1].

EP4 receptor antagonist 3

HY-138761 MedChemExpress Get quote Ask for price
Description: EP4 receptor antagonist 3 is a potent EP4 receptor antagonist, example 3,extracted from patent WO2010019796 A1. EP4 receptor antagonist 3 can be used for the reseacrh of EP4 receptor-mediated diseases, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer[1].

CB2 receptor antagonist 2

HY-149645 MedChemExpress Get quote Ask for price
Description: CB2 receptor antagonist 2 (compound 39) is a potent antagonist of CB2 with an IC50 value of 0.33 μM. CB2 receptor antagonist 2 has strong interactions with L17, W6.48, V6.51, and C7.42[1].

A2B receptor antagonist 1

HY-U00321 MedChemExpress 10mg 4440 EUR

A2A receptor antagonist 1

HY-102024 MedChemExpress 1mg 822.52 EUR
Description: A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively[1].

CB2 receptor antagonist 3

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Description: CB2 receptor antagonist 3 (compound (S)-1) is an inverse agonist of the cannabinoid receptor CB2R with Kd=39 nM. CB2 receptor antagonist 3 can be used as a tool to synthesize a variety of CB2R probes[1].

CB2 receptor antagonist 4

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Description: CB2 receptor antagonist 4 (compound (R)-1) is a CB2R-selective inverse agonist with a Kd value of 39 nM[1].

EP4 receptor antagonist 5

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Description: EP4 receptor antagonist 5 is a potent and selective prostanoid EP4 receptor antagonist that can reduce inflammation Freund’s adjuvant (CFA) model[1].

EP4 receptor antagonist 1

HY-133123 MedChemExpress 5 mg 1060.62 EUR
Description: EP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6.1 nM and 16.2 nM, respectively. IC50s >10 μM for human EP1, EP2,and EP3 receptors[1].

NK1 receptor antagonist 2

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Description: NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss[1].

CB2 receptor antagonist 1

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Description: Hexyl resorcinol derivative 29 has been proved to be a CB2 selective competitive antagonist / reverse agonist with good potency. Olivanol and 5- (2-methyloctane-2-yl) resorcinol derivatives 23 and 24 showed significant antinociceptive activity. Compound 24 was shown to activate cannabinoid and TRPV1 receptors.

A2A receptor antagonist 3

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Description: A2A receptor antagonist 3 (Example 92) is an adenosine A2a receptor antagonist with a Ki of 0.4 nM. A2A receptor antagonist 3 also binds to A2b, A1 and A3 receptor with Kis of 37, 107 and 1467 nM, respectively[1].

A2B receptor antagonist 2

HY-139314 MedChemExpress 100 mg 97.4 EUR
Description: A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively[1].

A2A receptor antagonist 2

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Description: A2A receptor antagonist 2 (Compound 57) is a potent, highly selective adenosine A2A receptor (A2AR) antagonist with an IC50 of 8.3 nM[1].

A2A receptor antagonist 1

MBS5785269-10mg MyBiosource 10(mg 240 EUR

A2A receptor antagonist 1

MBS5785269-1mg MyBiosource 1(mg 160 EUR

A2A receptor antagonist 1

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A2B receptor antagonist 2

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A2B receptor antagonist 2

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A2B receptor antagonist 2

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A2B receptor antagonist 1

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A2B receptor antagonist 1

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EP4 receptor antagonist 1

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EP4 receptor antagonist 1

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EP4 receptor antagonist 1

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A2A receptor antagonist 1

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A2A receptor antagonist 1

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A2A receptor antagonist 1

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A2A receptor antagonist 1

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A2A receptor antagonist 1

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EP4 receptor antagonist 3

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EP4 receptor antagonist 3

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EP4 receptor antagonist 1

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Description: EP4 receptor antagonist 1

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Description: EP4 receptor antagonist 1

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Description: EP4 receptor antagonist 1

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Description: EP4 receptor antagonist 1

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Description: EP4 receptor antagonist 1

A2B receptor antagonist 1

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Description: A2B receptor antagonist 1

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Description: A2B receptor antagonist 1

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Description: A2B receptor antagonist 1

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Description: A2B receptor antagonist 1

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Description: A2B receptor antagonist 1

For the pan traps, wolf spiders had been discovered to be the dominant spider species. No important variations had been noticed in the quantity of spiders caught in numerous coloured pans, suggesting that shade will not be an essential flower trait in regard to spider desire.

To the greatest of our information, this research is the first to suggest the time period 'flower-visiting spiders’ and conduct a scientific investigation of their range. However, that is preliminary analysis and additional research are required, particularly as biodiversity is commonly carefully linked to survey websites and ecotopes.

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